discoid lupus erythematosus
Quick Summary
Discoid lupus erythematosus is an autoimmune disorder that causes chronic inflammation, primarily affecting the skin. It is characterized by distinct, reddened patches covered with scales, often appearing on the face, neck, and scalp. This form of lupus does not typically involve internal organs, though in about 10 percent of cases, it can progress to the more severe systemic lupus erythematosus. The underlying cause of lupus is a malfunction of the immune system, where the body mistakenly produces autoantibodies that attack its own tissues, leading to inflammation and injury. While the exact reasons for this autoimmune response are not fully understood, genetic predisposition and environmental triggers are thought to play a role.1
Ask Britannica AI about this topic
Britannica doesn't have a full article on this topic, so we've curated a list of our relevant coverage.
- lupus erythematosus
Discoid lupus affects only the skin and does not usually involve internal organs. The term discoid refers to a rash of distinct reddened patches covered with grayish brown scales that may appear on the face, neck, and scalp. In about 10 percent of people with…
Read MoreDiscoid lupus affects only the skin and does not usually involve internal organs. The term discoid refers to a rash of distinct reddened patches covered with grayish brown scales that may appear on the face, neck, and scalp. In about 10 percent of people with…
Read More - connective tissue diseaseSystemic lupus erythematosus
…adults with the disease, (2) discoid lupus, an erythematous raised patchy eruption that heals with scarring and atrophy of the skin and may be found anywhere on the body, (3) Raynaud syndrome (see below), (4) photosensitivity, manifested by unusual skin reaction after exposure to sunlight, (5) nondeforming arthritis, (6) inflammation…
Read More…adults with the disease, (2) discoid lupus, an erythematous raised patchy eruption that heals with scarring and atrophy of the skin and may be found anywhere on the body, (3) Raynaud syndrome (see below), (4) photosensitivity, manifested by unusual skin reaction after exposure to sunlight, (5) nondeforming arthritis, (6) inflammation…
Read More