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The dermal papilla is a small, cone-shaped protrusion of the dermis that extends into the base of a hair follicle. It is composed of connective tissue and is crucial for hair growth. The epidermis of the hair follicle grows inward to surround a cluster of dermal cells, forming the dermal papilla.1

Nerves sensitive to heat, cold, pain, and pressure extend through the dermis and end in papillae within the skin. The dermal papilla plays a role in the cyclic activity of hair follicles, releasing from the epidermal matrix during the resting phase of hair growth. When a new growth cycle begins, the secondary germ proliferates and reinvests the dermal papilla, leading to the formation of a new hair.21

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