derivatization

chemistry

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July 17, 2026

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Derivatization is a chemical process where a compound is converted into a derivative. This is often done to make the compound easier to measure or analyze. For example, non-volatile substances can be transformed into volatile ones for gas chromatography. Many quantitative spectrophotometric methods also involve derivatization, where an analyte reacts with a reagent to form a strongly absorbing complex. This technique is crucial in analytical chemistry for identifying and quantifying substances.12

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Derivatization
In many analytical procedures it is necessary to convert the analyte chemically to another form to make its measurement possible. While infrared absorption techniques for organic analytes are usually direct methods, nearly all quantitative ultraviolet and visible absorption spectrophotometric methods are derivatizations in which…
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In many analytical procedures it is necessary to convert the analyte chemically to another form to make its measurement possible. While infrared absorption techniques for organic analytes are usually direct methods, nearly all quantitative ultraviolet and visible absorption spectrophotometric methods are derivatizations in which…
Read More