cytidine monophosphate

chemical compound

Also known as: CMP

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June 25, 2026

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Cytidine monophosphate (CMP) is a nucleotide composed of cytosine, ribose, and a phosphate group. It is a building block for ribonucleic acid (RNA), a molecule crucial for converting genetic information from DNA into proteins. CMP is also involved in cellular metabolism, particularly in the synthesis of phospholipids, where it acts as a precursor in reactions involving cytidine triphosphate (CTP). CTP is utilized in cells to incorporate cytidylic acid units into RNA and also participates in the formation of coenzymes essential for phospholipid synthesis.123

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metabolism
Formation of lipids
…catalyzed by a specific enzyme, CMP is displaced from CDP-diglyceride by one of three compounds—serine, inositol, or glycerol 1-phosphate—to form CMP and, respectively, phosphatidylserine, phosphatidylinositol (in [85b]), or 3-phosphatidyl-glycerol 1′-phosphate (PGP; in [85c]). These reactions differ from those of polysaccharide biosynthesis ([79], [82]) in that phosphate is retained in the…
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…catalyzed by a specific enzyme, CMP is displaced from CDP-diglyceride by one of three compounds—serine, inositol, or glycerol 1-phosphate—to form CMP and, respectively, phosphatidylserine, phosphatidylinositol (in [85b]), or 3-phosphatidyl-glycerol 1′-phosphate (PGP; in [85c]). These reactions differ from those of polysaccharide biosynthesis ([79], [82]) in that phosphate is retained in the…
Read More