cyclophosphamide

drug

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June 25, 2026

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Cyclophosphamide is an immunosuppressive and antineoplastic drug used in treating lymphomas and certain leukemias. It functions by suppressing the immune system. This type of drug is primarily utilized to prevent organ transplant rejection and manage autoimmune diseases. Cyclophosphamide's chemical formula is C₇H₁₅Cl₂N₂O₂P. It was first documented in 1960.12

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alkylating agent
…are nitrogen mustards (chlorambucil and cyclophosphamide), cisplatin, nitrosoureas (carmustine, lomustine, and semustine), alkylsulfonates (busulfan), ethyleneimines (thiotepa), and triazines (dacarbazine).
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…are nitrogen mustards (chlorambucil and cyclophosphamide), cisplatin, nitrosoureas (carmustine, lomustine, and semustine), alkylsulfonates (busulfan), ethyleneimines (thiotepa), and triazines (dacarbazine).
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granulomatosis and polyangiitis
…or chemotherapeutic drugs, such as cyclophosphamide or methotrexate, may be used. GPA can be brought into remission through prompt treatment, in some cases without long-term maintenance with drug therapies.
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…or chemotherapeutic drugs, such as cyclophosphamide or methotrexate, may be used. GPA can be brought into remission through prompt treatment, in some cases without long-term maintenance with drug therapies.
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