cyclic guanosine monophosphate

biochemistry

Also known as: cGMP

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Last updated

July 16, 2026

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Cyclic guanosine monophosphate (cGMP) is a molecule within cells that acts as a secondary messenger. It helps transmit signals from a cell's receptors to its targets, similar to how cyclic AMP (cAMP) functions.12

cGMP is a cyclic nucleotide derived from guanosine. These types of molecules, including cAMP and cGMP, are crucial for intracellular communication, relaying information received from outside the cell to various cellular processes. They enable rapid signal transmission throughout the cell.123

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PDE-5 inhibitor
…that causes the formation of cyclic guanosine monophosphate (cGMP); cGMP in turn causes the smooth muscle of the corpus cavernosum to relax, allowing blood to flow into the penis and produce an erection. PDE-5 breaks down cGMP, and so the PDE-5 inhibitors, by blocking the action of the enzyme, maintain…
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…that causes the formation of cyclic guanosine monophosphate (cGMP); cGMP in turn causes the smooth muscle of the corpus cavernosum to relax, allowing blood to flow into the penis and produce an erection. PDE-5 breaks down cGMP, and so the PDE-5 inhibitors, by blocking the action of the enzyme, maintain…
Read More