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Crossing over, also known as recombination, is a fundamental biological process that introduces genetic variation into populations. It occurs during meiosis, the process of forming sex cells (gametes).12

During crossing over, homologous chromosomes, one from each parent, pair up. Segments of these chromosomes are exchanged, creating new combinations of genes on the resulting chromatids. This exchange results in the formation of a cross-shaped structure called a Holliday junction.234

The outcome of crossing over is that each daughter cell produced during meiosis receives a unique combination of genetic material, ensuring that no two gametes are genetically identical to each other or to the parent cell. This genetic shuffling is crucial for evolution and adaptation.12

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