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The corticospinal tract is the largest of the descending spinal tracts, originating in the cerebral cortex and playing a crucial role in skilled voluntary movement. This tract contains about one million fibers and is a significant component of the brain's structure, passing through the internal capsule and crus cerebri.1

Most of these fibers (about 90%) cross over in the medulla oblongata, descending in the spinal cord to synapse with interneurons and motor neurons at various levels. The tract is vital for motor function, and its myelination during infancy correlates with the development of motor skills. Due to its extensive path through the central nervous system, the corticospinal tract is vulnerable to lesions, which can lead to contralateral hemiparesis, characterized by weakness and spasticity.1

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