congenital megacolon
Quick Summary
Congenital megacolon, also known as Hirschsprung disease, is a condition where the lower part of the large intestine lacks normal nerve fibers. This absence prevents peristalsis, the involuntary muscle contractions that move waste through the bowel. As a result, the intestine above the affected area works harder, causing its muscular walls to thicken and enlarge, leading to a distended and thickened colon. Symptoms in infants include a swollen abdomen and severe constipation. Diagnosis is typically made through a rectal biopsy, and surgical procedures can correct the condition.12
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- megacolon
…syndrome are congenital megacolon, or Hirschsprung disease, and acquired megacolon. In congenital megacolon, the lowermost portion of the large intestine is congenitally lacking in normal nerve fibres; thus, peristalsis, or involuntary contractions, of the muscles of this part of the intestine cannot occur, and the bowel’s contents are not pushed…
Read More…syndrome are congenital megacolon, or Hirschsprung disease, and acquired megacolon. In congenital megacolon, the lowermost portion of the large intestine is congenitally lacking in normal nerve fibres; thus, peristalsis, or involuntary contractions, of the muscles of this part of the intestine cannot occur, and the bowel’s contents are not pushed…
Read More - digestive system diseaseCongenital megacolon
Aganglionic megacolon, or Hirschsprung disease, is a condition of unknown cause that is characterized by the absence of ganglion cells and normal nerve fibres from the distal (or lower) 3 to 40 cm (1 to 16 inches) of the large intestine. Neuromuscular transmission…
Read MoreAganglionic megacolon, or Hirschsprung disease, is a condition of unknown cause that is characterized by the absence of ganglion cells and normal nerve fibres from the distal (or lower) 3 to 40 cm (1 to 16 inches) of the large intestine. Neuromuscular transmission…
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