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A commissure is an anatomical term referring to a point or line where two parts join or connect. This can be seen in structures like adjacent heart valves. In the brain and spinal cord, a commissure is a band of nerve tissue that connects different areas.1

For example, the corpus callosum is a thick band of white matter that connects the two cerebral hemispheres, allowing them to integrate information. The brain also has a "soft commissure," which is gray matter connecting the optic thalami across the third ventricle. Additionally, "postcommissures" are bands of white matter located at the back of the third ventricle.234

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