colpocephaly

Colpocephaly is a cephalic disorder characterized by the enlargement of the occipital horns, located at the rear of the lateral ventricles in the brain. This enlargement stems from the insufficient development of the posterior cerebrum. The exact cause is unknown, but it may be linked to anomalies within the uterine environment during the second trimester of pregnancy.1

Infants born with colpocephaly often exhibit microcephaly (small head size), intellectual disability, muscle spasms, and seizures. The severity of these symptoms and the overall prognosis are directly related to the degree of the brain's abnormality. The term "colpo-" itself is a combining form derived from the Greek word for "vagina" or "womb," but in the context of colpocephaly, it refers to a specific part of the brain's structure.123