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The coelom is a body cavity found in many animals, located between the digestive tract and the body wall. This cavity is lined with mesoderm, the middle of the three primary germ layers. The presence and development of a coelom are key characteristics used to classify animals, particularly within the Bilateria group.123

There are different ways a coelom can form. In schizocoelomates, the coelom develops from a splitting of the mesodermal mass during embryonic development. This is common in protostomes like mollusks and annelid worms. In contrast, deuterostomes often form their coelom through enterocoelic pouching, where the endoderm evaginates to create pouches that become the coelom.453

A true coelom offers significant advantages, such as suspending the digestive tract within the body, which allows for larger body sizes and more complex organ systems. It plays a crucial role in locomotion for some animals, like annelids, while in others, such as vertebrates, its primary function is suspension, supported by an internal skeleton.5

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