clomiphene

drug

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Last updated

July 20, 2026

Quick Summary

Clomiphene is a fertility drug that works by blocking estrogen receptors in the brain. This action prompts the hypothalamus to release gonadotropin-releasing hormone (GnRH), which then stimulates the pituitary gland to secrete follicle-stimulating hormone (FSH) and luteinizing hormone (LH). These hormones encourage the ovaries to release an egg, thereby stimulating ovulation. Clomiphene is classified as a centrally acting fertility drug and is used to help women who have difficulty becoming pregnant. It is also known as an antiestrogen because it interferes with the inhibitory feedback of estrogens on the pituitary gland.12

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antiestrogen
Clomiphene can be used as a fertility drug to stimulate ovulation in some women who are otherwise unable to become pregnant. It interferes with the inhibitory feedback of estrogens on the pituitary gland. This results in an increase in follicle-stimulating hormone and luteinizing hormone release;…
Read More
Clomiphene can be used as a fertility drug to stimulate ovulation in some women who are otherwise unable to become pregnant. It interferes with the inhibitory feedback of estrogens on the pituitary gland. This results in an increase in follicle-stimulating hormone and luteinizing hormone release;…
Read More