citrate

References

Images

A metabolic pathway diagram for Escherichia coli showing how various nutrients-including sugars, fats, glycerol, and amino acids-are broken down into intermediates like pyruvate and acetyl-CoA, leading to the production of energy and other metabolites such as lactate, glutamate, and succinate. Arrows indicate the flow of metabolites between compounds, with key nutrient sources and products highlighted in colored boxes.

citrate

chemical compound

Written by

The Information Architects of Encyclopaedia Britannica

Learn about this topic in these articles:

metabolism
Formation of coenzyme A, carbon dioxide, and reducing equivalent
…reacts with oxaloacetate to yield citrate and to liberate coenzyme A. This reaction [38] is catalyzed by citrate synthase. (As mentioned above, many of the compounds in living cells that take part in metabolic pathways exist as charged moieties, or anions, and are named as such.) Citrate undergoes isomerization (i.e.,…
Read More
…reacts with oxaloacetate to yield citrate and to liberate coenzyme A. This reaction [38] is catalyzed by citrate synthase. (As mentioned above, many of the compounds in living cells that take part in metabolic pathways exist as charged moieties, or anions, and are named as such.) Citrate undergoes isomerization (i.e.,…
Read More
metabolism
Energy state of the cell
…fuel, inhibition of glycolysis by citrate may be physiologically the more important means of control. Control by citrate, the first intermediate of the TCA cycle, which produces the bulk of the cellular ATP, is thus the same, in principle, as control through ATP.
Read More
…fuel, inhibition of glycolysis by citrate may be physiologically the more important means of control. Control by citrate, the first intermediate of the TCA cycle, which produces the bulk of the cellular ATP, is thus the same, in principle, as control through ATP.
Read More

plant
Principal pathways and cycles
The product, citrate, has three carboxylic acid groups—hence the name tricarboxylic acid cycle. Citrate is systematically catabolized (broken down) with progressive losses of successive carbon atoms as CO₂ into five-carbon and, finally, four-carbon, acids. The latter acid, oxaloacetate, begins the cycle again. With each oxidation reaction, a…
Read More
The product, citrate, has three carboxylic acid groups—hence the name tricarboxylic acid cycle. Citrate is systematically catabolized (broken down) with progressive losses of successive carbon atoms as CO₂ into five-carbon and, finally, four-carbon, acids. The latter acid, oxaloacetate, begins the cycle again. With each oxidation reaction, a…
Read More