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Cinchonism is a disorder that results from the excessive or prolonged use of cinchona bark or its alkaloids, such as quinine. This condition is characterized by temporary deafness, ringing in the ears (tinnitus), headache, dizziness, and skin rash.1

Cinchona is a genus of trees native to the Andes of South America. Certain species of cinchona bark contain quinine, which has historically been the primary treatment for malaria. While quinine is effective, a high level of it in the blood can lead to cinchonism.23

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  1. cinchonism
  2. cinchona
  3. antiprotozoal drug

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