chronic glomerulonephritis

Chronic glomerulonephritis, also known as Bright disease, is a progressive inflammation of the kidney's glomeruli and nephrons. These structures are vital for filtering waste from the blood to produce urine. This condition often follows acute or subacute stages of glomerulonephritis, though it can also develop independently.1

In chronic glomerulonephritis, the kidneys become small, shriveled, and largely replaced by scar tissue. This severe damage impairs the kidneys' ability to filter waste products, leading to a buildup of toxins in the blood, a condition known as uremia. Treatment focuses on managing blood pressure, dietary changes like fluid and salt restriction, and sometimes anti-inflammatory drugs. In advanced cases, dialysis may be necessary.1