cholinesterase
Quick Summary
Cholinesterase is an enzyme that plays a crucial role in the nervous system. It is primarily found at neuromuscular junctions and in cholinergic nerve endings. The main function of cholinesterase, specifically acetylcholinesterase, is to break down the neurotransmitter acetylcholine after it has transmitted nerve impulses. This breakdown is essential for regulating nerve signaling and preventing continuous stimulation.1234
There are different types of cholinesterase, including acetylcholinesterase and butyrylcholinesterase. Drugs that affect cholinesterase activity, known as anticholinesterases, can inhibit or mimic the action of acetylcholine. These drugs have various applications, from treating conditions like myasthenia gravis and Alzheimer disease to being used as insecticides or nerve agents.134
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- dimethoate
…insecticide that acts by inhibiting cholinesterases, enzymes involved in transmitting nerve impulses. Chemically, it is an organophosphate. Like all organophosphates it is related to the nerve gases and is among the most toxic of all pesticides to vertebrates, including humans. As a systemic, dimethoate is taken up into the roots…
Read More…insecticide that acts by inhibiting cholinesterases, enzymes involved in transmitting nerve impulses. Chemically, it is an organophosphate. Like all organophosphates it is related to the nerve gases and is among the most toxic of all pesticides to vertebrates, including humans. As a systemic, dimethoate is taken up into the roots…
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occupational diseaseOrganic compoundsCholinesterase inhibitors allow the accumulation of acetylcholine, causing symptoms related to parasympathetic overactivity, such as chest tightness, wheezing, blurring of vision, vomiting, diarrhea, abdominal pain, and in severe cases respiratory paralysis. Atropine and certain oximes counteract their effects.
Read MoreCholinesterase inhibitors allow the accumulation of acetylcholine, causing symptoms related to parasympathetic overactivity, such as chest tightness, wheezing, blurring of vision, vomiting, diarrhea, abdominal pain, and in severe cases respiratory paralysis. Atropine and certain oximes counteract their effects.
Read More- phorate
…insecticide that acts by inhibiting cholinesterases, enzymes involved in transmitting nerve impulses. Chemically, it is an organophosphate, O,O-diethyl S-(ethylthio)methyl phosphorodithioate. Like all organophosphates, it is related to the nerve gases and is among the most toxic of all pesticides to vertebrates, including humans.
Read More…insecticide that acts by inhibiting cholinesterases, enzymes involved in transmitting nerve impulses. Chemically, it is an organophosphate, O,O-diethyl S-(ethylthio)methyl phosphorodithioate. Like all organophosphates, it is related to the nerve gases and is among the most toxic of all pesticides to vertebrates, including humans.
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