chimeric mouse
Quick Summary
A chimeric mouse is created by introducing genetically modified mouse embryonic stem cells into an early mouse embryo. These modified cells can then contribute to the development of the resulting mouse, creating an organism composed of cells from both the original embryo and the introduced stem cells.
This process is crucial in medical research for creating "knockout mice," where specific genes are inactivated. By studying these mice, scientists can understand the function of individual genes and their role in various human diseases. This allows for the development of new therapies and a deeper understanding of biological processes. Mice are used due to their genetic similarity to humans and their short life cycles, enabling rapid study across generations.12
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