Britannica AI Icon

chelating agent

chemistry
Also known as: sequestering agent

Quick Summary

A chelating agent is a molecule that can bind to a central metal atom, forming a cyclic structure known as a chelate ring. This binding process is called chelation. Chelates are generally more stable than compounds without this ring structure, a phenomenon attributed to the chelate effect, which is related to an increase in entropy.1

Chelating agents are crucial in various applications:
* Medicine: They are used to treat metal poisoning by binding to toxic metal ions, such as lead or iron, rendering them harmless.12
* Industry and Laboratories: They serve as extractants for separating metals and as buffers or indicators in analytical chemistry.1
* Biology: Many natural substances, like chlorophyll and hemoglobin, are chelate compounds.1

The stability of a chelate depends on the number of attachments the ligand has to the metal ion and the size of the resulting ring structure, with five- or six-membered rings typically being the most stable.1

Summary created from Britannica articles using AI. AI can make mistakes, so verify using Britannica articles.
2 Britannica Sources
  1. chelate
  2. chelation therapy

Ask Britannica AI about this topic

Britannica doesn't have a full article on this topic, so we've curated a list of our relevant coverage.