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The cerebral aqueduct, also known as the aqueduct of Sylvius, is a canal within the midbrain that connects the third and fourth ventricles of the brain. This passageway is crucial for the flow of cerebrospinal fluid (CSF). CSF is a clear liquid that circulates throughout the brain and spinal cord, providing cushioning and maintaining stable pressure within the skull.1234

Obstruction of the cerebral aqueduct can lead to a buildup of CSF, a condition called hydrocephalus. This blockage can be congenital or acquired due to factors like tumors or meningitis. Hydrocephalus can cause increased intracranial pressure, leading to symptoms such as headaches, dementia, and vomiting.52

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