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The centrum is the main body of a vertebra, located ventral to the neural arch. This structure is a key component of the vertebral column, which protects the spinal cord and provides body support.12

In vertebrate development, the centrum originates from the sclerotome, a part of the mesodermal somites. These cells migrate to surround the notochord, forming the precursor, or blastema, of the centrum. This mesenchymal blastema then undergoes chondrification (turning into cartilage) and ossification (bone formation) to become the bony centrum of a mature vertebra. In higher vertebrates, the centra are separated by intervertebral disks, which act as shock absorbers.32

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