carcinogenesis
Quick Summary
Carcinogenesis is the process by which cancer is produced. It involves abnormal cell growth and a malfunction in the mechanisms controlling cell division and maturation. This transition from normal to cancerous cells is an evolutionary process driven by genetic changes.12
Carcinogens, agents that can cause cancer, interact with DNA in cells, interfering with normal function and leading to uncontrolled cell division and resistance to programmed cell death. These agents can be chemical, physical, or viral. For example, chemicals like polycyclic aromatic hydrocarbons found in tobacco smoke, or physical agents like UV radiation, can damage DNA.345
The development of cancer often involves precancerous stages, where abnormal cellular changes occur. These changes can accumulate over time, leading to the characteristics of cancer cells, such as limitless reproduction and the ability to invade and spread to distant tissues.24
Ask Britannica AI about this topic
Britannica doesn't have a full article on this topic, so we've curated a list of our relevant coverage.