carboxylation

chemical reaction

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June 22, 2026

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Carboxylation is a chemical reaction where a carboxyl group (-COOH) or carbon dioxide is introduced into a compound, forming a carboxylic acid. This process is the opposite of decarboxylation, which involves the removal of a carboxyl group from a molecule. Enzymes called carboxylases catalyze these reactions. Carbonylation is a related synthesis process that creates carbonyl compounds, often involving carbon monoxide. A carbonyl group itself is a carbon atom double-bonded to an oxygen atom, a key feature in many organic compounds like aldehydes and ketones.12345

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metabolism
Positive modulation
The carboxylation of pyruvate in higher organisms and the carboxylation of phosphoenolpyruvate in gut bacteria ccurs at a significant rate only if acetyl coenzyme A is present. Acetyl coenzyme A acts as a positive allosteric effector and is not broken down in the course of the…
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The carboxylation of pyruvate in higher organisms and the carboxylation of phosphoenolpyruvate in gut bacteria ccurs at a significant rate only if acetyl coenzyme A is present. Acetyl coenzyme A acts as a positive allosteric effector and is not broken down in the course of the…
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photosynthesis
Stage 1: Carboxylation
The initial incorporation of carbon dioxide, which is catalyzed by the enzyme ribulose 1,5-bisphosphate carboxylase (Rubisco), proceeds by the addition of carbon dioxide to the five-carbon compound ribulose 1,5-bisphosphate (RuBP) and the splitting of the resulting six-carbon compound into two molecules of PGA. This…
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The initial incorporation of carbon dioxide, which is catalyzed by the enzyme ribulose 1,5-bisphosphate carboxylase (Rubisco), proceeds by the addition of carbon dioxide to the five-carbon compound ribulose 1,5-bisphosphate (RuBP) and the splitting of the resulting six-carbon compound into two molecules of PGA. This…
Read More