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A bubo is an inflammatory swelling of a lymph gland, most commonly found in the groin, armpits, or neck. This symptom is characteristic of the bubonic plague, a serious infectious disease caused by the bacterium Yersinia pestis.12

Symptoms of bubonic plague typically manifest within a few days of infection and include fever, chills, headache, weakness, and fatigue. The hallmark symptom is the painful swelling of lymph nodes, forming buboes. If left untreated, the infection can progress to the bloodstream or lungs, resulting in more severe complications.3

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