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basal transcription factor

biology
Also known as: general transcription factor

Quick Summary

Basal transcription factors are essential proteins that enable RNA polymerase to initiate gene transcription in eukaryotes. They are the most basic set of proteins required for this process and include factors like TFIIA and TFIIB. These factors bind to specific DNA regions called promoters or directly to RNA polymerase, controlling when, where, and how efficiently genes are transcribed into RNA. Transcription factors are crucial for cell development, function, and response to disease, influencing cell fate and responding to external signals.12

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