back mutation
Quick Summary
A back mutation, also known as reversion, is a genetic change where a mutated gene returns to its original, or "wild type," condition. This process is the opposite of a forward mutation, which changes a gene from its wild type to a mutant form.12
While true reversion involves reversing the exact nucleotide change, a phenotypic reversion can occur through different mechanisms. These include a different nucleotide change that restores an amino acid with similar properties, or a second-site mutation in the same or a different gene that compensates for the original mutation's effect. These compensatory mutations can restore normal protein function or create alternative biochemical pathways.3
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- heredityGene mutation
…wild type is called a back mutation or reversion.
Read More…wild type is called a back mutation or reversion.
Read More - heredityRepair of mutation
Reverse mutation from the aberrant state of a gene back to its normal, or wild type, state can result in a number of possible molecular changes at the protein level. True reversion is the reversal of the original nucleotide change. However, phenotypic reversion can result…
Read MoreReverse mutation from the aberrant state of a gene back to its normal, or wild type, state can result in a number of possible molecular changes at the protein level. True reversion is the reversal of the original nucleotide change. However, phenotypic reversion can result…
Read More