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Autoimmune arthritis is a condition where the body's own immune system mistakenly attacks its tissues, leading to inflammation and damage, particularly in the joints. Rheumatoid arthritis is a common example, characterized by chronic inflammation of the synovial membranes that lubricate joints. This inflammation can erode cartilage and bone, causing pain, stiffness, swelling, and potentially leading to joint deformities and immobility.1234

While the exact cause is unknown, genetic predisposition and environmental factors like infection or trauma are thought to trigger this autoimmune response. The presence of autoantibodies, such as rheumatoid factor, is often associated with the disease, though not always diagnostic. Treatment focuses on managing symptoms and slowing disease progression, as there is no cure.412

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