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An atheromatous lesion, also known as an atheroma or fatty plaque, is a key component of atherosclerosis. This is a chronic disease where fats, cholesterol, calcium, and other substances build up in the inner lining of arteries, causing them to thicken and harden.

The process often begins with injury to the artery's inner layer, potentially caused by high cholesterol, high blood pressure, or smoking. This injury attracts cells and substances that accumulate, forming the atheroma. These plaques can narrow the artery, restricting blood flow and reducing oxygen supply to organs. If blood flow to the heart is blocked, it can cause a heart attack, and if it affects the brain, it can lead to a stroke. Atherosclerosis typically shows no symptoms until a significant blockage occurs.12

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  1. arteriosclerosis
  2. atherosclerosis

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