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atheroma

pathology
Also known as: fatty plaque

Quick Summary

An atheroma is an abnormal fatty deposit within an artery. It is a key component of atherosclerosis, a chronic disease where fats, cholesterol, calcium, and other substances build up in the inner lining of arteries. This buildup, forming an atheroma or plaque, can cause arteries to thicken and harden, losing elasticity.123

The process often begins with injury to the artery's inner layer, potentially caused by high cholesterol, high blood pressure, or smoking. Over time, these deposits accumulate, narrowing the artery and restricting blood flow. This can lead to serious complications such as heart attack or stroke. Atherosclerosis typically shows no symptoms until significant blockage occurs.324

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