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ascending midbrain reticular activating system

physiology
Also known as: ARAS

Quick Summary

The ascending reticular activating system (ARAS) is a crucial part of the brainstem and midbrain that regulates arousal and alertness. When this system is active, an individual is awake, alert, and attentive. Damage to the ARAS can lead to unresponsiveness, confusion, or unconsciousness, even if sensory pathways are intact.1

The ARAS receives input from various sensory pathways and projects to the cerebral cortex via the thalamus. Unlike primary sensory pathways that are specific to one sense, many ARAS cells respond to signals from any sensory modality. This system is fundamental to maintaining wakefulness and plays a role in the sleep-wake cycle. Moment-to-moment shifts in attention are thought to involve a diffuse thalamic projection system connected to the ARAS. The ARAS works in conjunction with the cerebral cortex and other brain regions to process sensory information and mobilize resources.1

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