aprotic solvent

chemical compound

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June 18, 2026

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An aprotic solvent is a chemical compound that is incapable of acting as a proton donor. These solvents do not have acidic or basic properties. Examples of aprotic solvents include hydrocarbons and their halogen derivatives. Some aprotic solvents, such as N,N-dimethylformamide and dimethyl sulfoxide, have high dielectric constants and are effective solvents for various substances. In these solvents, basic anions are poorly solvated, making them behave as very strong bases.123

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acid–base reaction
Nonaqueous solvents
…the reverse is true), and aprotic (in which both acidic and basic properties are almost entirely absent). Finally, concentrated aqueous acids are mentioned as an example—a particularly important one—of mixed solvents.
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…the reverse is true), and aprotic (in which both acidic and basic properties are almost entirely absent). Finally, concentrated aqueous acids are mentioned as an example—a particularly important one—of mixed solvents.
Read More