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apoprotein E
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apoprotein E

chemical compound
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Quick Summary

Apolipoprotein E (apoE) is a protein component of lipoproteins, which are complexes that transport lipids throughout the body. Lipoproteins are essential for moving fats derived from food or synthesized internally via the circulatory system.12

ApoE is found in several types of lipoproteins, including chylomicrons, very low-density lipoproteins (VLDL), and high-density lipoproteins (HDL). Its primary role involves the recognition of lipoproteins by receptors on cell surfaces, facilitating their uptake and processing. This function is crucial for cholesterol metabolism and transport within the body. High levels of certain lipoproteins can lead to atherosclerosis, a condition where deposits build up on artery walls, potentially causing heart attacks or strokes.12

Summary created from Britannica articles using AI. AI can make mistakes, so verify using Britannica articles.
2 Britannica Sources
  1. lipid - Functions, origins, and recycling of apolipoproteins
  2. lipid - High-density lipoproteins (HDL)

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