anti-inflammatory agent
Quick Summary
Anti-inflammatory agents are medications that reduce inflammation, pain, and fever. They primarily work by inhibiting the synthesis of prostaglandins, which are molecules that mediate these responses in the body.1
Two main types of anti-inflammatory agents are discussed:
- NSAIDs (Nonsteroidal Anti-inflammatory Drugs): These include common over-the-counter medications like ibuprofen and naproxen, as well as aspirin. They are generally used for short periods to manage mild pain and inflammation.1
- Glucocorticoids: These are steroid hormones produced by the adrenal gland, such as cortisol. They have potent anti-inflammatory and immunosuppressive actions and are used to treat conditions like asthma and inflammatory bowel disease.23
While NSAIDs reduce inflammation at its source, glucocorticoids work by inhibiting enzymes involved in the inflammatory pathway.24
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immune system disorderTreatment of type I allergic responsesSome, such as the anti-inflammatory cromolyn, prevent mast-cell granules from being discharged if administered before reexposure to antigen. For treatment of asthma and severe hay fever, such drugs are best administered by inhalation. The effects of histamine can be blocked by antihistamine agents that compete with histamine for binding…
Read MoreSome, such as the anti-inflammatory cromolyn, prevent mast-cell granules from being discharged if administered before reexposure to antigen. For treatment of asthma and severe hay fever, such drugs are best administered by inhalation. The effects of histamine can be blocked by antihistamine agents that compete with histamine for binding…
Read More- asthmaTreatment and management of asthma
…categorized into three main types: anti-inflammatory agents, which suppress inflammation; bronchodilators, which relax smooth muscle constriction and open the airways; and leukotriene receptor antagonists (LTRAs; sometimes called leukotriene modifiers), which interrupt the chemical signaling within the body that leads to constriction and inflammation. These medications may be taken on a…
Read More…categorized into three main types: anti-inflammatory agents, which suppress inflammation; bronchodilators, which relax smooth muscle constriction and open the airways; and leukotriene receptor antagonists (LTRAs; sometimes called leukotriene modifiers), which interrupt the chemical signaling within the body that leads to constriction and inflammation. These medications may be taken on a…
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inflammationChemical mediators of inflammationAnti-inflammatory drugs, such as aspirin, are effective in part because they inhibit an enzyme involved in prostaglandin synthesis. Prostaglandins are synthesized from arachidonic acid, as are the leukotrienes, another group of chemical mediators that have vasoactive properties.
Read MoreAnti-inflammatory drugs, such as aspirin, are effective in part because they inhibit an enzyme involved in prostaglandin synthesis. Prostaglandins are synthesized from arachidonic acid, as are the leukotrienes, another group of chemical mediators that have vasoactive properties.
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