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Anestrus is the period of sexual quiescence, or inactivity, between periods of sexual activity in cyclically breeding mammals. This is in contrast to estrus, which is the period when a female mammal is receptive to mating. During estrus, the uterine lining thickens in preparation for potential pregnancy, and the female may exhibit behavioral signals indicating readiness to mate. Some animals are monestrous, having only one estrus period per breeding season, while others are polyestrous and will cycle repeatedly if not impregnated. Males can detect females in heat through pheromones. Anestrus, therefore, represents the time outside of this fertile window.12

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