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Androstenedione is a steroid sex hormone that plays a role in the biosynthesis of testosterone and estrogen. It is produced in the testes, ovaries, and adrenal cortex. Cholesterol serves as the central precursor for all steroid hormones in vertebrates, including androstenedione. This hormone is an intermediate in the pathway from progesterone to androgens like testosterone in the testes, and to estrogens like estradiol in the ovaries. The body metabolizes steroid hormones, primarily in the liver, into inactive products that are then excreted.12

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