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aminoacyl-acceptor site
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aminoacyl-acceptor site

biochemistry
Also known as: A site
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Quick Summary

The aminoacyl-acceptor (A) site is a crucial location on the ribosome during protein synthesis. It's where incoming transfer RNA (tRNA) molecules, each carrying a specific amino acid, bind to the messenger RNA (mRNA) template. This binding is guided by the complementary base triplets between the mRNA and the tRNA. Once bound, the amino acid is transferred to the growing protein chain. After this transfer, the tRNA moves from the A site to the peptidyl-donor (P) site, making the A site available for the next aminoacyl-tRNA. This process is fundamental to translating the genetic code into functional proteins.1

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2 Britannica Sources
  1. transfer RNA
  2. metabolism - Synthesis of proteins

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