acyl chloride
Quick Summary
An acyl chloride is a chemical compound with the structure RCOCl, where R is an organic group and Cl is a chlorine atom. These compounds are derivatives of carboxylic acids and are characterized by a carbonyl group (C=O) bonded to a halogen atom. Acyl chlorides are highly reactive, making them useful in synthesizing other organic compounds, including esters, amides, and ketones.123
They are typically prepared by treating a carboxylic acid with a chlorinating agent like thionyl chloride. Acyl chlorides react readily with water, alcohols, and amines. For example, acetyl chloride (CH3COCl) is a common acyl chloride used in preparing acetyl derivatives. Due to their reactivity, acyl chlorides must be stored in airtight containers.134
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carboxylic acidHydrolysis of acid derivatives…acid derivatives to hydrolyze are acyl chlorides, which require only the addition of water. Carboxylic acid salts are converted to the corresponding acids instantaneously at room temperature simply on treatment with water and a strong acid such as hydrochloric acid (shown as H+ in the equations above). Carboxylic esters, nitriles,…
Read More…acid derivatives to hydrolyze are acyl chlorides, which require only the addition of water. Carboxylic acid salts are converted to the corresponding acids instantaneously at room temperature simply on treatment with water and a strong acid such as hydrochloric acid (shown as H+ in the equations above). Carboxylic esters, nitriles,…
Read More- carboxylic acidConversion to acid derivatives
…carboxyl group to the corresponding acyl chloride (RCOOH → RCOCl).
Read More…carboxyl group to the corresponding acyl chloride (RCOOH → RCOCl).
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