acetyl transacylase

enzyme

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July 23, 2026

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Acetyl transacylase is an enzyme involved in the synthesis of fatty acids. This process begins with acetyl coenzyme A (acetyl-CoA), a compound crucial in metabolism that acts as a coenzyme in biological acetylations.123

In fatty acid synthesis, acetyl-CoA is converted into malonyl coenzyme A. Acetyl transacylase, along with malonyl transacylase, facilitates the transfer of acetyl and malonyl groups to a molecule called acyl-carrier protein (ACP). These reactions are part of a larger pathway that ultimately builds fatty acids from smaller units.1

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metabolism
Fatty acids
…and [63b] are known as acetyl transacylase and malonyl transacylase, respectively. Acetyl-ACP and malonyl-ACP react in a reaction catalyzed by β-ketoacyl-ACP synthetase so that the acetyl moiety (CH₃CO―) is transferred to the malonyl moiety (⁻OOCH₂CO―). Simultaneously, the carbon dioxide fixed in step [62] is lost, leaving as a product a…
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…and [63b] are known as acetyl transacylase and malonyl transacylase, respectively. Acetyl-ACP and malonyl-ACP react in a reaction catalyzed by β-ketoacyl-ACP synthetase so that the acetyl moiety (CH₃CO―) is transferred to the malonyl moiety (⁻OOCH₂CO―). Simultaneously, the carbon dioxide fixed in step [62] is lost, leaving as a product a…
Read More