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acetoacetic ester synthesis
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acetoacetic ester synthesis

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Quick Summary

Acetoacetic ester synthesis is a chemical process that uses ethyl acetoacetate (CH₃COCH₂COOC₂H₅) as an intermediate to create various organic compounds. Ethyl acetoacetate is produced through the self-condensation of ethyl acetate.1

This ester can form sodium derivatives that are then alkylated or dialkylated. The resulting esters can be transformed into ketones or carboxylic acids. Ethyl acetoacetate is also used in condensation reactions to synthesize compounds like pyridines, quinolines, furans, pyrazoles, pyrroles, and purines.1

Industrially, ethyl acetoacetate is important for manufacturing synthetic drugs and dyes. It is a colorless, fragrant liquid with a boiling point of 180.4 °C (356.7 °F).1

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4 Britannica Sources
  1. ethyl acetoacetate
  2. carboxylic acid - Synthesis
  3. acetoacetic ester
  4. aldehyde - Synthesis of aldehydes

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