acetazolamide

Acetazolamide, which was developed by scientists at Lederle Laboratories (now a part of Wyeth Pharmaceuticals, Inc.), became the first of a class of diuretics that serve as carbonic anhydrase inhibitors. In an attempt to produce a carbonic anhydrase inhibitor more effective than acetazolamide, chlorothiazide was…

Acetazolamide may be used for potassium-aggravated myotonia and other myotonias caused by mutations in SCN4A. Individuals with such conditions may also benefit from mexiletine.