acamprosate

drug

Also known as: calcium acetylhomotaurinate

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July 16, 2026

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Acamprosate, also known as calcium acetylhomotaurinate, is a drug used in the treatment of alcoholism. It functions as a modulator of gamma-aminobutyric acid (GABA) and N-methyl-D-aspartate (NMDA) receptors. Studies have shown acamprosate to be effective in reducing relapse rates in alcohol abuse over periods up to a year, though long-term effectiveness has not been established. It is considered a physiological treatment, often used alongside psychological methods, and is part of a broader approach to alcoholism treatment that includes detoxification and relapse prevention education.1

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alcoholism
Physiological therapies
…naltrexone (an opiate antagonist) and acamprosate, or calcium acetylhomotaurinate (a modulator of gamma-aminobutyric acid [GABA] and N-methyl-D-aspartate [NMDA] receptors), have, like disulfiram, been effective in reducing relapse over periods up to a year. But there is no evidence that either of these agents reduces the risk of relapse over the…
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…naltrexone (an opiate antagonist) and acamprosate, or calcium acetylhomotaurinate (a modulator of gamma-aminobutyric acid [GABA] and N-methyl-D-aspartate [NMDA] receptors), have, like disulfiram, been effective in reducing relapse over periods up to a year. But there is no evidence that either of these agents reduces the risk of relapse over the…
Read More