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Nitrogen is fundamental to life because it is needed to make DNA and RNA, which carry genetic information, and amino acids, which form proteins—all of which are essential to the composition of living organisms. Nitrogen is also a core component of chlorophyll, which absorbs energy from light in photosynthetic organisms, and adenosine triphosphate (ATP), the primary energy-carrying molecule found in the cells of plants and animals.

Earth is enveloped by an atmosphere that consists of about 78 percent nitrogen gas (N2). The vast majority of living organisms, however, are not able to use nitrogen in its gaseous form. To render this form usable, it must undergo nitrogen fixation, wherein the relatively inert gas is combined chemically with other elements to form more-reactive nitrogen compounds such as ammonia, nitrates, or nitrites. This process is carried out by certain bacteria and archaea. Ammonia and nitrates are absorbed by plants. Animals then obtain nitrogen by consuming plants or other organisms. The circulation of nitrogen in various forms through nature is known as the nitrogen cycle.