Which structures connect the cerebrum to the spinal cord in the brainstem?

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The brainstem serves as the primary communication pathway between the cerebrum and the spinal cord. Anatomically, it is composed of three main sections that facilitate this connection:1

  • Midbrain (mesencephalon): The uppermost section of the brainstem, located directly beneath the diencephalon.21
  • Pons (metencephalon): The middle section, which connects the midbrain to the medulla oblongata.231
  • Medulla oblongata (myelencephalon): The lowest portion of the brainstem, which is continuous with the spinal cord at the base of the skull.231

Nearly all nerve pathways carrying information to and from the cerebrum pass through these regions via tracts, such as the corticospinal tract, which transmits motor commands from the cerebral cortex to the spinal cord.314