Which organs and structures can be affected by respiratory diseases?

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Respiratory diseases can affect a wide range of structures and organs involved in the process of breathing and gas exchange. These include:

  • Upper Airway: The nose, paranasal cavities (sinuses), pharynx, and larynx.123
  • Lower Airway: The trachea, bronchi, bronchioles, and alveolar ducts.123
  • Lung Tissue: The lungs, including the parenchyma (gas-exchanging tissue) and the alveoli.13
  • Supporting Structures: The pleura (the membrane covering the lungs), the thoracic cage, and respiratory muscles such as the diaphragm and intercostal muscles.123
  • Circulatory and Lymphatic Systems: Because the lungs contain a vast network of capillaries, respiratory diseases often involve the heart, blood vessels, and lymph nodes.1243
  • Other Organs: Certain systemic conditions can cause respiratory involvement alongside other organs, such as the kidneys.56