Britannica
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Which conditions can cause optic atrophy?
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atrophy
One example of atrophy is the progressive loss of bone that occurs in osteoporosis (normal bone shown on left; osteoporotic bone shown on right).
Optic atrophy refers to the degeneration of the optic nerve resulting from damage to retinal ganglion cells. This condition can be triggered by a variety of pathological factors, including:
- Ocular and Systemic Diseases: Glaucoma and serious retina disorders that destroy significant neural tissue are common causes.12
- Inflammation: Optic neuritis, which may be associated with multiple sclerosis, can lead to nerve damage.12
- Compression: Tumours, such as those affecting the pituitary gland, can press on the optic nerve or chiasm.12
- Vascular and Physical Trauma: Damage can result from blood vessel diseases or direct physical injury.1
- Toxic and Nutritional Factors: Exposure to certain drugs, chemicals, or nutritional deficiencies may cause atrophy.12
- Hereditary Conditions: Genetic disorders, such as Leber hereditary optic neuropathy, are also known causes.1
Treatment focuses on addressing the underlying condition to prevent further nerve degeneration.12