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Leber’s disease

pathology
Also known as: LHON, Leber hereditary optic neuropathy

Quick Summary

Leber hereditary optic neuropathy (LHON) is a type of optic atrophy, which is the degeneration of the optic nerve. This condition is hereditary and primarily affects males between the ages of 15 and 25. While vision recovery is sometimes possible, it is rarely complete. LHON is a form of mitochondrial disease, which are hereditary conditions resulting from the failure of mitochondria, the energy-producing organelles within cells. These diseases can manifest at any age and have diverse symptoms, including visual impairments like optic atrophy. Treatment focuses on managing the underlying condition to prevent further damage to the optic nerve.12

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2 Britannica Sources
  1. optic atrophy
  2. mitochondrial disease

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