Wernicke-Korsakoff syndrome

Wernicke-Korsakoff syndrome (common in alcoholics) results from a thiamine (vitamin B₁) deficiency and consists of eye movement disorders, cerebellar incoordination, memory loss, and peripheral neuropathy. If peripheral neuropathy is the only symptom of thiamine deficiency, the disorder is called beriberi. In each case, replacement of…

…may occur in combination with Wernicke disease, which results from a deficiency of thiamine and is characterized by damage to nerves in both the central and peripheral nervous system.