Salk vaccine
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The Salk vaccine, developed by American physician Jonas Salk, is a polio vaccine that uses inactivated poliovirus to prevent the disease. Polio is a viral infectious disease that can cause paralysis, though most infected individuals show no symptoms. In the mid-20th century, hundreds of thousands of children were affected annually by polio.123
Salk's vaccine, tested in 1952 and released in 1955, was administered by injection and significantly reduced polio incidence. A second vaccine, the Sabin vaccine, which uses live attenuated virus and is given orally, was developed later. Widespread vaccination has led to the elimination of polio from most of the world, with only Afghanistan and Pakistan remaining endemic as of 2022.1453
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polioTreatment and vaccinationā¦(IPV), also known as the Salk vaccine, named for its inventor, Jonas Salk; and the oral poliovirus vaccine (OPV), or Sabin vaccine, named for its inventor, Albert Sabin. IPV, based on killed, or inactivated, poliovirus serotypes 1, 2, and 3, was the first vaccine to break the scourge of polioā¦
Read Moreā¦(IPV), also known as the Salk vaccine, named for its inventor, Jonas Salk; and the oral poliovirus vaccine (OPV), or Sabin vaccine, named for its inventor, Albert Sabin. IPV, based on killed, or inactivated, poliovirus serotypes 1, 2, and 3, was the first vaccine to break the scourge of polioā¦
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infectious diseaseImmunizationā¦of inactivated polio virus (Salk vaccine) generates less production of serum antibody and induces only a temporary systemic immunity; it may not produce substantial local gastrointestinal immunity and, therefore, may not prevent the carrying of the virus in the gastrointestinal tract. Live, attenuated, oral polio virus (Sabin vaccine) inducesā¦
Read Moreā¦of inactivated polio virus (Salk vaccine) generates less production of serum antibody and induces only a temporary systemic immunity; it may not produce substantial local gastrointestinal immunity and, therefore, may not prevent the carrying of the virus in the gastrointestinal tract. Live, attenuated, oral polio virus (Sabin vaccine) inducesā¦
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virusPreventionā¦available are the ākilledā (Salk) vaccine, composed of inactivated virus of the three types, and the āliveā (Sabin) vaccine, composed of genetically attenuated viruses of the three types. In developed countries these vaccines, which were introduced in the 1950s, have lowered the incidence of paralysis resulting from polio. Theā¦
Read Moreā¦available are the ākilledā (Salk) vaccine, composed of inactivated virus of the three types, and the āliveā (Sabin) vaccine, composed of genetically attenuated viruses of the three types. In developed countries these vaccines, which were introduced in the 1950s, have lowered the incidence of paralysis resulting from polio. Theā¦
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