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Rho-GAM
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Rho-GAM

biochemistry
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Quick Summary

Rho-GAM is a human immune serum globulin used to prevent Rh hemolytic disease of the newborn. This condition can occur when an Rh-negative mother carries an Rh-positive fetus. During pregnancy or delivery, fetal blood cells can enter the mother's bloodstream, causing her immune system to produce anti-Rh antibodies. These antibodies can then attack the red blood cells of subsequent Rh-positive fetuses, leading to serious illness or death. Rho-GAM is administered to Rh-negative mothers after delivery of an Rh-positive infant, or after miscarriage or abortion, to prevent the formation of these harmful antibodies. It works by destroying any fetal blood cells before the mother's immune system can develop antibodies.12

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2 Britannica Sources
  1. infectious disease - Rho-GAM
  2. Rh blood group system

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