PIWI-interacting RNA
biochemistry
Also known as: piRNA
Quick Summary
PIWI-interacting RNAs (piRNAs) are small noncoding RNA molecules, typically 26 to 31 nucleotides in length, found in most animals. Their primary function is to regulate the expression of transposons, also known as "jumping genes," by preventing them from being transcribed in germ cells (sperm and eggs). This regulation is crucial for maintaining the integrity of the genome. piRNAs achieve this by being complementary to specific transposon sequences, allowing them to target and silence these mobile genetic elements.1
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